Prognosis of Acute Myocardial Infarction (AMI) among diabetic patients is different than with non-diabetics. Diabetic patients have statistically significantly grater mortality in comparison with non-diabetics who suffered AMI. Mortality among women with diabetes is greater than among men with diabetes. Goal of this paper was to examine differences, in percents, of lethal outcomes from AMI among patients treated in hospitals, diabetics and non-diabetics and gender differences within lethal outcomes of AMI separately in both groups. Research is performed in two groups of diabetics and non-diabetics who are treated at the ward for Internal diseases in Cantonal Hospital Zenica during 1991, 1993 and 1996. In this period there was 506 patients with AMI treated, among them 94 (18,58%) had diabetes, and there was 412 (81,42%) non-diabetics. Among 94 diabetics there were 19 (20,21%) of lethal outcomes and among 412 non-diabetics was 114 (27,67%) lethal outcomes. Among non-diabetics with AMI there were 296 (17,84%) male patients, and 116 (28,16%) female patients. From 296 male patients in total 65 (21,95%) had lethal outcome, and from 116 female patients lethal outcome was found in 49 (42,24%) cases. Among 94 diabetics with AMI there was 41 male patients (43,62%), and 53 female (56,38%). From 41 males lethal outcome had 3 (7,3%), and from 53 females lethal outcome was in 16 (30,2%) cases. Among diabetics and non-diabetics with AMI we did not found statistically significant differences in percentages of lethal outcomes. In the group of non-diabetics with AMI women had, in comparison to males statistically significant larger number of lethal outcomes.In the group of diabetics with AMI lethal outcome among women in comparison to males was 4 times more frequent.