Age, sex, incidence and mortality of patients with acute myocardial infarction (AMI) has been followed up («hot pursuit») in ten-years period, during the war in Bosnia (from 1992 to 1995), including also a year before and five after. The influence of war-induced stress and some circumstances (depressive status, starvation, physical activity) on the incidence and mortality of acute coronary artery disease was perceived. Cardiac enzymes and electrocardiograms werw controlled to all patients with AMI. Echocardiography has been investigated if it was necessary for diagnosis and prognosis. A total of 1949 patients with AMI were hospitalized. There were 66% of male patients. Increase of incidence of AMI in the first war year continues with gradually decrese until the last year of war with revise of increase in postwar years. A total of 365 patients died and mortality was 19%. In the prewar year mortality was only 10%. Maximal mortality was noticed in the first war year (22%) and in second postwar year (25%). Majority of patients i.e. 55% were within 56 to 70 years of age. Patients aged 40 years of less represented only 4% of total population with mortality of 2,6%. Maximal mortality (26%) was in population aged 65 years and more (38% of total population). Female mortality (23%) was higher than male's (16%). In annual review male mortality was balanced, always below 20%, after initial increase in 1st war year. Opposite, female mortality course was irregular with two peaks in 1st war (31%) and 2nd postwar (41%) year and decrease (8%), was noticed during the war (below man's mortality value). Increase of incidence and mortality in the first year of war can be explained by war-induced acute stress and by migration of displaced people. Rise of female mortality occurred as results of mental stress, which was induced by war conditions and aggravating family circumstances in postwar period (bad socio-economic status: high degrees of unemployment and absence of psychic and social prosperity). Decrease of female mortality can be explained by facultative engagement in war activities.