Background: Obesity can be an important factor in development of cardiovascular disease. Many studies imply that distribution of fat tissue, especially visceral fat tissue is the more important risk factor then total amount of fat tissue in obese patients. Today, several methods were applied in estimation of visceral fat tissue. Most reliable dates were available from computerized tomograpy (CT) and magnetic resonance imaging (MRI). Due to high expenses and possible damaging effects of those methods, visceral fat tissue attempted to be examined by ultrasound. Aim of this study was estimation of ultrasound applicability in measuring of subcutaneous and visceral fat tissue in routine abdominal examination. Patients and methods: in a period of one year, we examined 50 patients: 26 male, 24 female, without significant difference in age (average age of male patients was 48.7 and for female patients 51.2, body mass index for male 28.4 kg/m2; female 29.8 kg/m2). All patients underwent antropometical and ultrasound measurements and patients with clinical indications underwent CT examination. Results were presented in tables, graphics and pictures. Conclusion: observed results implies that ultrasound is less precise than CT but applicable in measurement of thickness of subcutaneous and visceral fat tissue as a risk factor for cardiovascular disease. Ultrasound could be applied not just experimentally but in daily praxis to patients on abdominal examination, for routine measurement of subcutaneous and visceral fat tissue thickness without longer duration of examination.